… role of ion channels during viral lifecycles, describe the recently identified ion channel drugs
that … that ion channel inhibitors represent a new antiviral strategy. Whilst toxicity profiles for …

… -selective ion channel that is required for virus replication and is an established antiviral target.
… mutations, and ongoing efforts to develop new antivirals that target resistant forms of M2. …

… preparations that target ion channels, improving our understanding of the role of ion channels
in viral … may reveal their potential as targets of new, safe drugs with broad antiviral activity. …

… with small-molecule inhibitors may provide an attractive option in antiviral development.
The … (and many other ion channels) makes them suitable targets for the cage compound …

… hindered the development of effective vaccines or antiviral drugs against it. Hence, there is
a continuous need for identification of new antiviral targets. HIV exploits specific host proteins …

… for new antiviral countermeasures. The M2 protein of influenza A is a proton-gated, proton-…
ion channel, which is essential for influenza replication and an established antiviral target. …

… E5 oncoprotein forms a virus-coded ion channel or viroporin that was sensitive to the …
E5 channel activity represents a viable drug target with potential for both antiviral and anti-…

… as ion channels on the viral membranes, similar to how they function in host cells, we
propose that 2-E channel may represent a new class of dual-function targets against SARS-CoV-2. …

… Given the importance of these viroporins and others in related viruses 14 , this suggests that
ion channel inhibitors might provide an attractive principle for future antiviral therapy. Future …

… , the wide variety of molecular targets for antiviral therapy. The reproductive cycle of many
… against the ion channels of viruses, other compounds with pronounced antiviral activity but …